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Acute monoblastic leukemia

Acute monoblastic leukemia Causes

There are a number of risk factor that were identified that largely contribute to the development of AML. Among these include pre-leukemic blood disorders, exposure to chemotherapy, ionizinf radiation, occupation chemical exposure, and some congenital conditions such as Down syndrome.

Acute monoblastic leukemia Definition

Acute monoblastic leukemia otherwise known as acute monocytic leukemia is an acute type of myeloid leukemia. For patients to be considered a victim of AML-M5, he must have more than 20% blasts in the marrow. Monoblasts are largely distinguished for displaying a rough, circular nucleus and a delicate lacy chromatin.

Acute monoblastic leukemia Diagnosis

The first clue of AML includes abnormal result of the patient's blood count. AML also presents isolated decrease in red blood cells, platelets and even an abnormally low white blood cell count. A bone marrow examination can also be performed to further identify the type of blood cells that have displayed abnormality.

Acute monoblastic leukemia Symptoms and Signs

Among the usual indicators of acute monoblastic leukemia include asthenia or generalized weakness, pallor, unexplained fever, dizziness and other respiratory symptoms.

Acute monoblastic leukemia Treatment

Like other forms of blood cancer, AML treatment would largely consist of chemotherapy, which is divided into two phases: the induction and postremission therapy. Induction is administered to induce complete and lasting remission by reducing the leukemic cells to untraceable levels. Consolidation aims to eliminate any existing or residual diseases.

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