Adenosine monophosphate deaminase
Adenosine monophosphate deaminase Causes
The AMD deficiency may be asymptomatic or it can also be caused by exercise induced cramping or myalgias. For symptomatic patients, they don't accumulate ammonia during exercise as most people normally do.
Adenosine monophosphate deaminase Definition
Adenosine monophosphate deaminase (AMD) is a type of muscle-specific deficiency that is a common cause of many exercise-induced myopathy and is one of the most common causes of metabolic myopathy among human beings.
Adenosine monophosphate deaminase Diagnosis
The diagnosis for AMD remains to be quite difficult since it is generally nonspecific manifestations that can cross a number of medical specialties and the existence of disease variants. Urinary uric acid and creatinine ratio can become valuable and simple tests can imply diagnostic possibility of metabolic-related disorders.
Adenosine monophosphate deaminase Symptoms and Signs
The key indicators of AMD include the existence of drusens that start to enlarge. Blurry central vision is also one of the symptoms and patients should undergo visual acuity test to determine if the central vision is lost.
Adenosine monophosphate deaminase Treatment
Treatments for AMD involve exercise modulation for patients as well as to closely monitor physical activities. Symptomatic relief can also be achieved by administering correct dosage of ribose which is taken orally, dosage depends of the body weight of the patient.