Aldosteronism, Primary
Aldosteronism, Primary Causes
Though the adrenal glands each only have about half the size of the human thumb, it basically dictates a number of functions of the body. This include regulating the metabolism, blood pressure, the immune system, among a number of other essential functions. The most common cause of this medical condition is a benign growth in the adrenal gland or what is known as aldosteronoma, or Conn's syndrome. Other underlying causes may include highly rare genetic mutations, overactivity of the glands, and cancerous growths in the cortex of the adrenal glands.
Aldosteronism, Primary Definition
Primary aldosteronism is a medical condition, where the adrenal glands of the body produce too much of the aldosterone hormone, which causes the body lose potassium and retain sodium. In general, sodium and potassium work together to aid in maintaining the right balance of fluids in the human body, help in transmitting nerve impulses, as well as contract and relax the muscles. However, the excess in aldosterone results to sodium retention, retaining excess water and the increase of blood pressure and blood volume.
Aldosteronism, Primary Diagnosis
The primary basis for the diagnosis of this condition is the high blood pressure and the very low levels of potassium that does no respond to medications. Several tests are conducted to confirm the diagnosis, including oral salt loading, saline loading and Fludrocortisone suppression test.
Aldosteronism, Primary Symptoms and Signs
In the case of primary aldosteroinism, high blood pressure does not respond completely to medication, and this is the most common symptom of the disease. Other signs include headaches, fatigue, muscle cramps and weakness, temporary paralysis, excessive thirsts, excessive urination, tingling and pricking sensation and numbness.
Aldosteronism, Primary Treatment
Treatment approaches for the primary aldosteronism would greatly depend on the underlying cause. This may include a combination of certain medications and lifestyle changes that include healthier diet and regular exercise to help regulate the blood pressure.