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Amyloidosis



Amyloidosis Causes


The cause of primary amyloidosis is unknown, but it begins in your bone marrow. In accumulation to producing red and white blood cells and platelets, your bone marrow creates antibodies, proteins that protect you against infection and disease.


Amyloidosis Definition


Amyloidosis is a unique and potentially deadly disease that takes place when substances called amyloid proteins build up in your organs; which areabnormal proteins commonly formed by cells in your bone marrow that can be deposited in any tissue or organ.


Amyloidosis Diagnosis


Your doctor may conduct a physical exam and a variety of tests, including blood and urine tests. Although blood or urine tests may detect an abnormal protein — which could denote amyloidosis, the only definitive test for amyloidosis is a tissue biopsy


Amyloidosis Symptoms and Signs


Symptoms of this disease depend on the organs that were affected. Symptoms include: Swelling of your ankles and legs, numbness or tingling in your hands or feet, weight loss, weakness, diarrhea, shortness of breath, harsh fatigue, and difficulty swallowing.


Amyloidosis Treatment


For primary amyloidosis, some of medications include: Peripheral blood stem cell transplantation and medicines. Peripheral blood stem cell relocation involves chemotherapy and transfusion of previously collected immature blood cells (stem cells) with the goal to replace diseased or damaged marrow.


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