Autoimmune hemolytic anemia
Autoimmune hemolytic anemia Definition
Autoimmune hemolytic anemia it is a kind of hemolytic anemia where in the immune system of the body that attacks its own red blood cells (RBCs) which leads to the destruction of the red blood cell which is called as hemolysis. On the RBC's surface antibodies and related complement system components become permanent. With anti-globulin test the antibodies can be noticed also referred to as the direct Coombs test. Methyl-dopa and flaurabine drugs can induce AIHA.
Autoimmune hemolytic anemia Prognosis
Usually in young children it is temporary and self-limiting which happens within 3 months caused by an earlier viral infection but constant/chronic types can last longer.
Autoimmune hemolytic anemia Subtypes
Warm AIHA Idiopathic Systemic lupus erythematosus Evans' syndrome (antiplatelet antibodies and haemolytic antibodies) Chronic lymphocytic leukemia Drugs (methyldopa) Cold AIHA Idiopathic cold hemagglutinin syndrome Infectious mononucleosis Paroxysmal cold hemoglobinuria (rare) Lymphoma
Autoimmune hemolytic anemia Symptoms and Signs
Anemia Hemolytic anemia A - state that is distinguished by anemia because of the red blood cell's destruction.