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Autoimmune peripheral neuropathy



Autoimmune peripheral neuropathy Causes


The causes are generally grouped as follows: Genetic diseases: Friedreich's ataxia, Charcot-Marie-Tooth syndrome Metabolic/Endocrine: diabetes mellitus, failure of chronic renal, porphyria, amyloidosis, failure of the liver, hypothyroidism Toxic causes: alcohol abuse, drugs (vincristine, phenytoin, isoniazid), organic metals, heavy metals Inflammatory/swelling ailments: Guillain-Barr? syndrome, systemic lupus erythematosis, leprosy, Sj?gren's syndrome Vitamin deficit conditions: vitamin B12, vitamin A, vitamin E, thiamin Others: malignant disease, HIV, radiation, chemotherapy A lot of secondary nervous system ailments may exhibit similarly to muscle complications (myopathesis) also it is essential to develop approaches for evaluating sensory and motor troubles in patients so that accurate diagnosis can be done by a physician.


Autoimmune peripheral neuropathy Definition


Autoimmune peripheral neuropathy is a term for the nerves of the secondary nervous system being damaged that can result from either diseases of the nerve or from the systemic illness side-effects. Secondary neuropathies differ in their presentation and origin and can affect the neuromuscular or nerve junction.


Autoimmune peripheral neuropathy Treatment


There are a lot of treatment approaches for peripheral neuropathy that are suggestive or symptomatic. Several recent studies in animal prototypes has exhibited that neurotrophin-3 can go against the demyelination evident in some peripheral neuropathies.


Autoimmune peripheral neuropathy Types


Widespread peripheral neuropathy is balanced and commonly because of various systematic illnesses and ailment processes that affect the entire peripheral nervous system and divided in numerous categories: Distal axonopathies are caused by several metabolic or neuron’s toxic derangement. Myelinopathies are results from primary attack on the myelin resulting to an acute stopping of impulse conduction. Neuronopathies results from the damage of peripheral nervous system (PNS) neurons.


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