Central Diabetes Insipidus
Central Diabetes Insipidus Causes
Central diabetes insipidus is generally caused by the body's decreased production of vasopressin, a hormone that aids in the regulation of the body's water. It can also be caused by lack of the hormone, as well as the failure to release this hormone into one's bloodstream by the pituitary gland. Other causes include damage on the hypothalamus during surgery, brain injury, tumor, tuberculosis, aneurysm, and several forms of meningitis.
Central Diabetes Insipidus Definition
Central diabetes insipidus is the body's deficiency of the antidiuretic hormone, causing too much production of extremely dilute urine. It is uncommon, and involves intense thirst and over urination. The condition indicates the kidney's inability to balance urine concentration.
Central Diabetes Insipidus Diagnosis
Urinalysis will illustrate low concentration of the salt present in one's urine. Water restriction test allows the diagnosis of how well one's kidney works, as well as the amount of urine produced. Blood tests are also done to check for plasma sodium concentration.
Central Diabetes Insipidus Symptoms and Signs
Indicators can start slowly or abruptly at all ages. Frequently, the only signs are excessive production of urine and extreme thirst. An individual can drink large quantities of fluid to compensate the fluid lost by urination. The favored drink is often cold water. If compensation isn't probable, dehydration may rapidly follow, causing shock and low blood pressure. In children, this condition may interfere with eating, appetite, weight, as well as growth. It can also present vomiting, diarrhea, or fever.
Central Diabetes Insipidus Treatment
Desmopressin or vasopressin can be taken a few times daily. The condition can sometimes be controlled through medicines that stimulate vasopressin hormone production, but these medications are not likely to alleviate symptoms totally for people with severe condition.