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Cicatricial pemphigoid



Cicatricial pemphigoid Causes


Like any other autoimmune disease, environmental factors mixed with genetic vulnerability lead to the growth of autoantibodies that can cause cicatricial pemphigoid.


Cicatricial pemphigoid Definition


Cicatricial pemphigoid is a comparatively rare blistering disease involving the mucous membranes of the eyes, mouth, throat, nose, and genitals. The disease is an autoimmune disease wherein the immune system generates antibodies that attack certain proteins that attach the epidermal cells to each other. The disrupted connection causes the cell to separate from the skin's lower layers, thus blisters form.


Cicatricial pemphigoid Diagnosis


Doctors typically identify cicatricial pemphigoid through its characteristic blisters, but it is analyzed with certainty by skin sample examination. At times, doctors make use of “special chemical stains” that permit the visibility of antibody deposits under a microscope.


Cicatricial pemphigoid Symptoms and Signs


Some common symptoms of cicatricial pemphigoid include inflamed eyes, red eyes, mucous membrane blistering and scarring, and red swollen mucous membrane.


Cicatricial pemphigoid Treatment


The kind of treatment will generally depend on the severity of the disease. Corticosteroids in high dose are often a mainstay treatment. A patient can also go through plasmapheresis, which is a process of filtering antibodies from one's blood. Gold salt injections are sometimes used. Antibiotics may also be needed in treating infections of rupture blisters.


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