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Congenital insensitivity to pain with anhidrosis



Congenital insensitivity to pain with anhidrosis Causes


CIPA is primarily caused by genetic mutations, which can prevent the development of nerve cells which are mainly responsible for transmission of pain, cold and heat signals to the brain.


Congenital insensitivity to pain with anhidrosis Definition


Congenital insensitivity to pain with anhidrosis (CIPA) is a identified as an extremely rare genetic disorder that primarily affects the nervous system, preventing the sensations of cold, heat and pain. An individual afflicted with CIPA will not be able to detect pain or even differentiate intense temperatures.


Congenital insensitivity to pain with anhidrosis Diagnosis


Diagnosis would largely be dependent on the symptoms and reported lack of sensation by the patients. Since there are no physical manifestation of this condition, diagnosis will mostly be based on medical history of the patient. Supporting laboratory test may follow.


Congenital insensitivity to pain with anhidrosis Symptoms and Signs


Patients who suffer with suffer such disorder are likely to inflict injury on themselves in varying ways that would normally be avoid by feeling pain. Among the key indicators of congenital insensitivity to pain with anhidrosis are painless injuries, lack of pain sensation, scarring and infection of the tongue, bone fractures, and joint deformities.


Congenital insensitivity to pain with anhidrosis Treatment


There are no existing treatments for cases of congenital insensitivity to pain with anhidrosis as this is known as an incurable medical condition.


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