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Cutis laxa



Cutis laxa Causes


The underlying cause of cutis laxa is still not known and probably variable. Some theories include low lysyl oxidase activity, abnormal copper metabolism/copper deficiency, decreased elastin gene expression, increased elastase activity and immune-mediated mechanisms. Surgical Care


Cutis laxa Definition


Cutis laxa (CL) is an extremely rare disease that can either be acquired or inherited disorder of the connective tissue. This is characterized by marked inelasticity of the skin that usually hangs in folds. In both inherited and acquired cutis laxa, the internal organs may also be affected.


Cutis laxa Diagnosis


There are actually no definite laboratory findings for cutis laxa. Chest radiography may be also be done to check for possible pulmonary involvement.


Cutis laxa Symptoms and Signs


Primary symptoms include abnormally loss skin that hangs in fold and inelastic, skin fragility, prone to bruises, large bowels due to the its effect on the gastrointestinal tract along with emphysema, congestive heart failure, cardiomegaly, and even osteoporosis.


Cutis laxa Treatment


There are no treatments that currently exist to prevent the progression of the disease. Surgical procedures may be conducted to correct skin folds, and facial defects.


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