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Dentinogenesis imperfecta



Dentinogenesis imperfecta Causes


Dentinogenesis imperfecta is a genetic disorder thus it is caused by abnormal mutations in the DSPP gene that affects the production of protein essential for development of normal and strong teeth. Dentin which makes up the protective middle layer of the teeth is the part usually affected thus making the teeth susceptible to easy wear and decay.


Dentinogenesis imperfecta Definition


Dentinogenesis imperfecta is a disorder of tooth development brought about by abnormal genetic mutations in the DSPP gene. It causes discolorations in teeth and development of abnormally weak dentin causing teeth to break easily, and break easily as well. It is otherwise called as hereditary Opalescent Dentin. Researchers have identified three types of this disease.


Dentinogenesis imperfecta Diagnosis


Diagnosis of Dentinogenesis involves careful examination of patients dental history as it can provide clues on how severely fragile the teeth of a person are. Evaluation of the physical appearance of the teeth and laboratory exams are also administered.


Dentinogenesis imperfecta Symptoms and Signs


Patients who suffer this disease often have strong teeth discolorations, blue-gray or yellow-brown. Tooth decay can also be a symptom of having such disease. Teetch will have irregular dentital tubules with bigger diameter, Visible areasof uncalcified matrix and sometimes odontoblasts in dentin are visible.


Dentinogenesis imperfecta Treatment


Routine restorative techniques like intra-coronal restorations can be applied to treat mild to moderate Dentinogenesis imperfecta. But in severe cases with significant enamel fracturing and fast wearing of the teeth, full coverage of the crown is the treatment that can be effectively used such as using porcelain fused to special metal crowns. To effectively correct discoloration, bleaching is reported to be a good option. Of course, before any treatment is administered it is wise to have a dentist ascertain what type of Dentinogenesis imperfecta has affected the patient.


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