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Evans' Syndrome

Evans' Syndrome Causes

The cause of evan's disease is through autoimmune response of the body. The alteration of immune responds id not yet known.

Evans' Syndrome Definition

Evans' Syndrome is a disorder that refers to an autoimmune disease. It means that the patient's antibodies attack their own blood products like the red blood cells and platelet. It is commonly cause by the two autoimmune disorders, the Autoimmune hemolytic anemia (a condition in which the red blood cells are destroyed by an autoimmune process). And the immune thrombocytopenic purpura (a condition in which the platelets are destroyed by autoimmune process.)

Evans' Syndrome Diagnosis

The diagnosis of this disorder is through blood exams, not just to identify haemolytic anaemia and immune thrombocytopenic purpura, but it also identify for positive direct antiglobulin test (DAT). Some antibodies may occur directed against immune cells has indicate better term of this disorder.

Evans' Syndrome Symptoms and Signs

The symptoms that the patient with evan's syndrome may experience the same symptoms of thrombocytopenia and anemia, such as bleeding, bruising, dizziness and low RBC and platelet count in complete blood count.

Evans' Syndrome Treatment

First treatment in patient with evan's disease is glucocorticoid corticosteroids or intravenous immunoglobulin, must be given immediately especially for children with autoimmune hemolytic anemia. Immunosuppressive drugs are used, or in combination with glucocorticoid corticosteroids or intravenous immunoglobulin if the initial treatment relapse. A surgical procedure called splenectomy is also used but has short term benefit to the patient. For a permanent cure the stem cell transplantation (SCT) is done to the patient.

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