Free Online Database Of Diseases, Illnesses & Ailments


Factor V Leiden Mutation

Factor V Leiden Mutation Causes

Factor V Leiden mutation is caused by the alteration of a variant of factor V, wherein its Leiden aspect can't be inactivated by an activated Protein C. The disorder is commonly hereditary. If an individual inherits one copy of the defective gene, they are called heterozygous; a person who inherits two copies of the defective gene is known as homozygous. Homozygous individuals are at a higher risk of vein blood clots that can travel to their lungs.

Factor V Leiden Mutation Definition

Factor V Leiden mutation is a widespread clotting disorder caused by the mutation of a gene in the clotting of Factor V. The mutation results to Factor V responding more gradually to Protein C. Protein C is an anti-clotting aspect that usually controls Factor V activity. Consequently, individuals with Factor V Leiden mutation have increased risks of thrombophilia or blood clots.

Factor V Leiden Mutation Diagnosis

Factor V Leiden mutation can be detected through special blood tests. Physical examination and medical history may also be used for diagnosis.

Factor V Leiden Mutation Symptoms and Signs

The disorder includes three common symptoms: blood clots, thrombosis, and deep vein thrombosis.

Factor V Leiden Mutation Treatment

If there is development of blood clots, treatment can include anticoagulant or anti-clotting medicines such as Coumadin or warfarin.

Most Viewed Pages

Recent Searches

Our Visitors Ask About

Medical News