Hypercortisolism
Hypercortisolism Causes
Cushing's syndrome can develop from a cause that originates outside of the body (exogenous Cushing's syndrome). Taking corticosteroid medications in high doses over an extended period of time may lead to Cushing's syndrome. These medications, such as prednisone, dexamethasone (Decadron) and methylprednisolone (Medrol), have the same effects as does the cortisol produced by one's body.
Hypercortisolism Definition
Hypercortisolism is a condition that arises from an excess of cortisol, a hormone produced by the adrenal glands. Sometimes called hypercortisolism, Cushing's syndrome can occur when the adrenal glands, located above the kidneys, make too much cortisol. It may also develop if the person is taking high doses of cortisol-like medications (corticosteroids) for a prolonged period.
Hypercortisolism Diagnosis
Cushing's can be sometimes difficult to diagnose. The doctor will conduct a physical exam, looking for signs of Cushing's syndrome. He or she may suspect Cushing's syndrome if the patient displays symptoms.
Hypercortisolism Symptoms and Signs
Some symptoms of hypercortisolism include: moon face (round, red, and full); buffalo hump (a collection of fat between the shoulders); central obesity with protruding abdomen and thin extremities; weight gain; weakness; backache; headache; acne or superficial skin infections; thin skin with easy bruising; thirst; increased urination; purple striations on the skin of the abdomen, thighs, and breasts; mental changes; impotence or cessation of menses; and facial hair growth.
Hypercortisolism Treatment
Treatments for Cushing's syndrome are designed to lower the high level of cortisol in the body. The best treatment for the person depends on the cause of the syndrome.