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Hyperoxaluria Causes

High levels of oxalate in blood mainly cause Hyperoxaluria. Excessive oxalate can be the result of different factors including genetic defect, diet, altered transport mechanism of the oxalate, fat malabsorption, and other diseases.

Hyperoxaluria Definition

Hyperoxaluria is a condition in which there is emission of excessive quantity of ‘oxalate' in one's urine. Oxalate is basically organic salt that forms soluble salt when combined with potassium and sodium, but when joint with calcium, it generates insoluble product that's found in kidney stones. Mild types of the condition are comparatively common, and may cause the formation of kidney stones. Bigger quantities of the oxalate in urine may be due to intestinal diseases that cause over-absorption of the oxalate.

Hyperoxaluria Diagnosis

Diagnosis include complete physical exam, including history. Tests are also done to confirm diagnosis.

Hyperoxaluria Symptoms and Signs

The initial indications of the condition can appear at any point in time, starting from birth to an individual's early adulthood. The symptoms can vary from subtle to severe. Depending on severity, initial sign is usually kidney stones. The presence of kidney stones will include symptoms like blood in urine, sudden or severe abdominal pain, chills and fever, pain during urination, and urge for frequent urination.

Hyperoxaluria Treatment

Treatment options include medications, dietary modifications, and high intake of fluid. Pyridoxine is a medication administered for reducing oxalate amounts produced by the liver. Citrate and neutral phosphates are also efficient in diminishing calcium oxalate stone and crystals in urine.

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