Hypocortisolism
Hypocortisolism Causes
Hypocortisolism occurs when the cortex is damaged and doesn't produce its hormones in adequate quantities. Doctors refer to the condition concerning damage to the adrenal glands as primary adrenal insufficiency. The failure of the adrenal glands to produce adrenocortical hormones is most commonly the result of the body attacking itself (autoimmune disease). For unknown reasons, the immune system views the adrenal cortex as foreign, something to attack and destroy.
Hypocortisolism Definition
Hypocortisolism, or Addison's disease, is a disorder that results in the body producing insufficient amounts of certain hormones produced by the adrenal glands
Hypocortisolism Diagnosis
The patient may undergo tests such as blood test, ACTH stimulation test, insulin-induced hypoglycemia test, and imaging tests.
Hypocortisolism Symptoms and Signs
Symptoms of this disorder usually develop slowly and may include: muscle weakness and fatigue, weight loss and decreased appetite, darkening of the skin (hyperpigmentation), low blood pressure, salt craving, low blood sugar (hypoglycemia), nausea, diarrhea, vomiting, irritability, and depression.
Hypocortisolism Treatment
Treatment may involve taking prescription corticosteroids. Because the body isn't producing sufficient steroid hormones, the doctor may have the patient take one or more hormones to replace the deficiency. Cortisol is replaced with hydrocortisone (Cortef), prednisone or cortisone. Fludrocortisone (Florinef) replaces aldosterone, which controls the body's sodium and potassium needs and keeps your blood pressure normal.