Leukocyte adhesion deficiency syndrome
Leukocyte adhesion deficiency syndrome Causes
Leukocyte adhesion deficiency syndrome is an inherited molecular dysfunction in the chromosome 21. This defect generates a non-functioning protein that in turn hinders the flow of other nutrients in the blood stream which are supposed to fight infections.
Leukocyte adhesion deficiency syndrome Definition
Leukocyte-adhesion deficiency syndrome is an autosomal recessive disorder that causes recurrent infections in the different parts of the body. It has two distinct genotypes known as type I and type II. Type II is known to create fewer infections but greater delay in developmental.
Leukocyte adhesion deficiency syndrome Diagnosis
Patients undergo several immune function tests, and results would show high levels of neutrophils which are already harmful to the bloodstream.
Leukocyte adhesion deficiency syndrome Symptoms and Signs
Persons with the said disease already experience bacterial problems during the neonatal period. Diseases such as pneumonia, gingivitis and peritonitis are usual and become life-threatening since the affected infant is still unable to fight against the invading pathogens.
Leukocyte adhesion deficiency syndrome Treatment
The disease is cured by bone marrow transplant and gene therapy.