McCune-Albright Syndrome
McCune-Albright Syndrome Causes
The individual with the syndrome usually has a mutated gene in which he or she has more than one cell populations that have dissimilar genetic makeup.
McCune-Albright Syndrome Definition
McCune-Albright syndrome is also known as polyostotic fibrous dysplasia. It is a genetic condition with disorder of the bones, pigmentation of skin, and premature puberty with hormonal problems.
McCune-Albright Syndrome Diagnosis
The existence of the syndrome is suspect when an individual reaches puberty prematurely, has Fibrous dysplasia, or Caf?-au-lait spots. However, the syndrome may not show until the patient is near puberty or it may be diagnosed during infancy with evident bone disorder and increased secretions of endocrine from several glands.
McCune-Albright Syndrome Symptoms and Signs
Patients have bone fracture and deformed legs, arms, and skin. They also have abnormal skin pigmentation and reaches puberty prematurely with rapid growth rate.
McCune-Albright Syndrome Treatment
In 2005, a teenager underwent an emergency procedure during which the doctors surgically removed an abnormal growth of bone from her face. The bone was was 16 ounds. It was followed by a series of operations that has improved the child's face to a more normal proportion.