Merkel Cell Cancer
Merkel Cell Cancer Causes
There is no definite cause of Merkel cell cancer, but recent research indicates a genetic origin of the disease.
Merkel Cell Cancer Definition
Merkel cell cancer is a rare form of cancer characterized by a bluish-red or flesh-colored nodule on the skin, particularly on the face, head, or neck of affected patients. It is also known as neuroendocrine carcinoma of the skin, and typically occurs in the elderly.
Merkel Cell Cancer Diagnosis
To determine Merkel cell cancer, a physical exam may be done to look for abnormal freckles, moles, pigmentations or growths on the patient's skin. To confirm the diagnosis, a biopsy may be performed to microscopically examine the affected tissue. A sentinel node biopsy may also be recommended to determine the extent of the disease and to ascertain if the cancer has spread beyond the skin. Additional diagnostic tests include a chest X-ray and a CT (computerized tomography) scan to determine other areas of the body affected with the cancer.
Merkel Cell Cancer Symptoms and Signs
A hallmark sign of Merkel cell cancer is the appearance of a rapidly growing nodule on the skin. This nodule (or more appropriately, tumor) is painless, and typically appears in shades of blue, purple, or red. Most Merkel cell tumors occur on the face, neck, or head, but may also grow elsewhere in the body. If the cancer has spread to other parts of the body, the patient may experience pain, fatigue, or swollen lymph nodes.
Merkel Cell Cancer Treatment
Surgery may be done to attempt to remove the tumor as well as a thin border of skin surrounding the cancerous tissue. If the cancer has spread to the lymph nodes, a lymph node dissection may also be done. In addition, Merkel cell cancer may be treated with radiation therapy and chemotherapy.