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Mobius syndrome



Mobius syndrome Causes


The disease is caused by the abnormal development of the cranial nerves, usually cranial nerves VI and VII, though there are times that cranial nerves V and VIII are also affected.


Mobius syndrome Definition


Named after German neurologist Paul Julius Mobius, Mobius/Moebius syndrome is an extremely neurological disorder.


Mobius syndrome Diagnosis


Infants with mobious syndrome can be identified at birth. A mask-like expression, known as bilateral facial palsy, is usually detected during crying or laughing. This is due to paresis of the sixth and seventh cranial nerves.


Mobius syndrome Symptoms and Signs


For patients whose cranial nerve VI is affected, reduction of the lateral gaze occurs. On the other hand, patients will suffer from bilateral facial palsy if the cranial nerve II is affected. Bilateral facial palsy is a mask-like expressionless face where the upper lip is often retracted due to muscle shrinkage. Hear loss may be experienced by those whose cranial VII is affected.


Mobius syndrome Treatment


Mobious syndrome does not have a known single course of medical treatment; treatment is therefore supportive and dependent on the symptoms. Feeding tubes or special bottles may be required for infants to maintain adequate nutrition. Meanwhile, surgery ma be required to correct crossed eyes, improve limb and jaw deformities and to protect the cornea.


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