Monomelic Amyotrophy
Monomelic Amyotrophy Causes
The exact cause of monomelic amyotrophy remains unknown. However, current theories point to the following as possible contributing factors: viral infections; vascular insufficiency (inadequate blood supply) of the spinal cord; strenuous physical activity; recent trauma or injury; radiation injury; as well as atrophy of the spinal cord.
Monomelic Amyotrophy Definition
Monomelic amyotrophy (or MMA) pertains to a rare disorder of the motor neurons, which are a group of nerves responsible for controlling voluntary muscles.
Monomelic Amyotrophy Diagnosis
Diagnostic tests for monomelic amyotrophy include: a thorough medical exam; medical history; electromyography or EMG; as well as standard imaging studies such as magnetic resonance imaging (EMG) and computer computed tomography (CT) scan.
Monomelic Amyotrophy Symptoms and Signs
Monomelic amyotrophy may exhibit the following symptoms: weakness or wasting of a single limb; weakness in the hand muscles; lower arm muscle weakness; grip weakness; clawed hand; as well as wasting of the hand and arm muscles. In spite of these symptoms, however, monomelic amyotrophy rarely presents with any pain.
Monomelic Amyotrophy Treatment
There is no definite cure for monomelic amyotrophy. Treatment is mostly supportive, designed to help affected individuals optimize muscle function as well as manage any resulting disability. Rehabilitation measures are integrated in overall therapy, including strengthening exercises and hand coordination training. In some extreme cases, orthopedic intervention may be necessary.