Multiple endocrine neoplasia type 1
Multiple endocrine neoplasia type 1 Causes
MEN1 is genetic in which patients inherit a mutation in a tumor suppressor gene called MEN1 on band 11q13. Protein and menin are among these genes.
Multiple endocrine neoplasia type 1 Definition
Sometimes called multiple endocrine adenomatosis or Wemer's syndrome, Multiple endocrine neoplasia type 1 (MEN1) is an inherited disorder affecting the endocrine glands. Occurring only in about 3 to 20 persons out of 100,000, MEN1 is quite rare but affects both sexes equally and has no geographical, ethnic, or racial preferences.
Multiple endocrine neoplasia type 1 Diagnosis
Depending on the clinical appearance, a skin biopsy may or may not be required. Skin findings may be used to aid in establishing the diagnosis of MEN1.
Multiple endocrine neoplasia type 1 Symptoms and Signs
MEN1 patients develop cutaneous tumors but can go unnoticed because they are subtle in appareance. Said tumors include multiple angiofibromas, collagenomas, and lipomas.
Multiple endocrine neoplasia type 1 Treatment
Some patients may opt for a surgery to remove the cutaneous tumors. The larger ones called angiofibromas, involve a variety of methods for people with tuberous sclerosis. Said methods include shave excision, dermabrasion, and carbon dioxide laser.