Muscular dystrophy, Duchenne and Becker type
Muscular dystrophy, Duchenne and Becker type Causes
DMD is caused by a mutation in a specific gene within the X chromosome that provides instructions for the formation of the dystrophin protein. Dystrophin is an important structural component of muscle tissue.
Muscular dystrophy, Duchenne and Becker type Definition
Duchenne muscular dystrophy is characterized by decreasing muscle mass and progressive loss of muscle function in male children.
Muscular dystrophy, Duchenne and Becker type Diagnosis
A CPK test, DNA test, muscle biopsy, and prenatal tests are the typical procedures related to the diagnosis of DMD.
Muscular dystrophy, Duchenne and Becker type Symptoms and Signs
Among male children before age 6, symptoms such as progressive muscle weakness of the les and pelvis associated with a loss of muscle mass is observed. The condition may eventually spread to the arms, neck, and other areas. An enlarged calf muscles, low strength and endurance levels, and difficulties in standing up and walking on stairs are among the early signs of DMD.
Muscular dystrophy, Duchenne and Becker type Treatment
Along with other forms of muscular dystrophy, DMD has no known cure although recent stem-cell research is showing promising vectors that may replace damaged muscle tissue. Controlling the symptoms to maximize the quality of life is the aim of treatments. The use of corcosteroids may defer the severity of symptoms. Mild, non-jarring physical activity, physical therapy, orthopedic appliances, and appropriate respiratory support may be recommended to patients.