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Myasthenia gravis congenital



Myasthenia gravis congenital Causes


The symptoms of the disease mainly weakness, is brought about by circulating antibodies that obstruct acetylcholine receptors at the post-synaptic neuromuscular junction, restraining the stimulative effect of the neurotransmitter acetylcholine.


Myasthenia gravis congenital Definition


A neuromuscular disease, Myasthenia gravis is an autoimmune disorder that can lead to unpredictable muscle weakness and fatigability. The term is coined from Greek and Latin terms, which literally means serious muscle weakness.


Myasthenia gravis congenital Diagnosis


It can be difficult to diagnose MG because the symptoms can be understated and hard to identify from both normal variants and other neurological disorders. Easy fatigability can be detected through a thorough physical examination. An assumed diagnosis may require a blood test serology. This will aid in identifying antibodies against the acetylcholine receptor.


Myasthenia gravis congenital Symptoms and Signs


Muscle weakness is the trait of myasthenia gravis, which is known to increase during periods of activity and improves after periods of rest. Other muscles such as those that control eye and eyelid movement, facial expression, talking, chewing and swallowing are also vulnerable.


Myasthenia gravis congenital Treatment


Medication and/or surgery are the known treatments for myasthenia gravis congenital. Cholinesterase inhibitors are tested medications that directly improve muscle function. Immunosuppressant drugs can also lessen the autoimmune process. Surgical methods such as thymectomy are carried out to treat MG. Emergency treatments include plasmapheresis or IVIG. Any of these may be done as a temporary measure to eliminate antibodies from the blood circulation.


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