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Neural tube defect, folate-sensitive

Neural tube defect, folate-sensitive Causes

Neural tube defects may result from exposure to a teratogen. It may also be a part of a multiple malformation syndrome. Neural tube defects that are not caused by teratogen exposure or associated with any malformation are assumed to be caused by a combination of environmental and genetic factors. Lack of folate (folic acid) in a pregnant mother's diet is a contributing factor in the occurrence of many neural tube defects according to several research studies.

Neural tube defect, folate-sensitive Definition

Neural Tube Defect, folate-sensitive Neural tube defect is a medical condition pertaining to any defect occurring in the neural tube. These are the most common and highly devastating as well as disabling birth defect. Spina bifida is an example of a neural tube defect. Neurolation is a part of organogenesis (development of internal organs of a body) in vertebrate embryos. Any interruption or anomaly during this process will produce neural tube defects in a fetus.

Neural tube defect, folate-sensitive Symptoms and Signs

Some of the presentations brought about by a neural tube defect are the following: * Increased head circumference * Dysmorphic features * Lump over the base of the back * Laryngeal paresis * Leg paralysis * Stridor * Bowel dysfunction * Foot deformities * Tuft of hair on the lower back

Neural tube defect, folate-sensitive Treatment

Some neural tube defects require no treatment; however prompt neurosurgical repair and proper treatment can help improve the condition of a patient. Though, most neural tube defects cause critical and permanent disability.

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