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Neuroleptic Malignant Syndrome

Neuroleptic Malignant Syndrome Causes

The fundamental causative factor for Neuroleptic malignant syndrome is antipsychotic drug and all other types of neuroleptic medications; the higher the dosage the more likely to suffer from this neurological disorder.

Neuroleptic Malignant Syndrome Definition

Neuroleptic malignant syndrome is a critical, life-threatening neurological disorder usually due to an adverse reaction neuroleptic or antipsychotic drugs.

Neuroleptic Malignant Syndrome Diagnosis

Clinical manifestations combined with increased Creatine Phosphokinase (CPK) level can confirm diagnosis of Neuroleptic Malignant Syndrome.

Neuroleptic Malignant Syndrome Symptoms and Signs

Some of the most common symptoms observed in a person suffering form Neuroleptic malignant syndrome are the following: * High fever * Muscle rigidity or involuntary movement or contraction of muscles that is uncontrollable * Autonomic instability * Cognitive changes like delirium * Unstable blood pressure * Profuse sweating * Rapid heart rate * Rapid breathing * Tremor * Seizure * Swallowing difficulties * Speech difficulties * Excessive salivation or drooling

Neuroleptic Malignant Syndrome Treatment

Supportive treatment is necessary for this disorder; initial action for the purpose of treatment is to discontinue administering the antipsychotic drug to the patient. Intensive care is needed in many cases and supportive care should be maintained at the minimum level. There may be necessary treatments in order to oppose the specific effects of the disorder including circulatory support and electroconvulsive therapy in case medication fails to improve the condition.

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