Omenn Syndrome
Omenn Syndrome Causes
Omenn syndrome is genetically inherited.
Omenn Syndrome Definition
Omenn syndrome is a severe combined immunodeficiency associated with mutations in the recombination activating genes, affecting both B-cells and T-cells.
Omenn Syndrome Symptoms and Signs
Patients may experience shedding of the skin's outer layer, reddening of the skin, recurrent diarrhea, persistent bacterial infections, elevated count of white blood cells, enlarged liver and spleen, and swelling of lymph nodes.
Omenn Syndrome Treatment
Patients sometimes undergo a bone marrow transplantation and cord blood stem cells.