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Palmoplantar Keratoderma



Palmoplantar Keratoderma Causes


This medical condition is inherited that is passed down from parents to children. It is an autosomal dominant disorder that would usually occur in all generations of the family. The disease can also be a an autosomal recessive condition where both parents are contributors of the mutated gene.


Palmoplantar Keratoderma Definition


Keratoderma is actually a term that literally means a marked skin thickening. On the other hand, Palmoplantar refers to the skin located on the soles of the feet as well as the palms of the hands. More often than not, this medical condition can be a condition of an internal abnormality.


Palmoplantar Keratoderma Diagnosis


While this disease is not a life threatening condition, early diagnosis is important to be able to administer immediate treatment to prevent the disease from worsening. Diagnosis is usually done through molecular diagnosis, which will show gene variations.


Palmoplantar Keratoderma Symptoms and Signs


Symptoms include hyperhidosis, thickened nails, aberrant keratotic lesions – all symptoms may worsen as the patient ages.


Palmoplantar Keratoderma Treatment


Treatment for Keratolytics include 5-10% salicylic acid in a form of a ointment base. Dermatophyte infections should to be treated immediately. However, the treatment needs to be administered in a lifelong basis to better manage the symptoms that are associated with the disease.


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