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Peripheral Vascular Disease



Peripheral Vascular Disease Causes


Smoking - tobacco use in any form is the single most important modifiable cause of PAD internationally. Diabetes Mellitus which increased risk of PAOD 2-4X by causing endothelial and smooth muscle cell dysfunction in peripheral arteries. Dyslipidemia is elevation of total cholesterol, LDL cholesterol, and triglyceride levels each have been correlated with accelerated PAOD.


Peripheral Vascular Disease Definition


Peripheral vascular disease also known as peripheral vascular disease (PVD) and peripheral artery disease (PAD) is a collator for all diseases caused by the obstruction of large peripheral arteries, which can result from atherosclerosis, inflammatory processes leading to stenosis, an embolism or thrombus formation.


Peripheral Vascular Disease Diagnosis


Modern multislice computerized tomography (CT) scanners provide direct imaging of the arterial system as an alternative to angiography. CT has complete evaluation of the aorta and lower limb arteries without the need for an angiogram's arterial injection of contrast agent.


Peripheral Vascular Disease Symptoms and Signs


Claudication is a pain, weakness, or cramping in muscles due to decreased blood flow; Sores, wounds, or ulcers that heal slowly or not at all; Noticeable change in color (blueness or paleness) or temperature (coolness) when compared to the other limb; Diminished hair and nail growth on affected limb and digits.


Peripheral Vascular Disease Treatment


Dependent on the severity of the disease, the following steps can be taken: Conservative measures include Smoking cessation (cigarettes promote PAOD and are a risk factor for cardiovascular disease). Angioplasty (PTA or percutaneous transluminal angioplasty) could be done on solitary lesions in large arteries, such as the femoral artery.


Drugs used for treatment of Peripheral Vascular Disease


Trental

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