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POEMS Syndrome

POEMS Syndrome Causes

The cause of POEMS syndrome is not known. Research studies believe the involvement of an overgrowth of bone marrow cells produce chemicals damaging other parts of a person's body. The syndrome is not inherited or contagious.

POEMS Syndrome Definition

POEMS syndrome is a disorder of the blood. Its name stands for the syndrome's most common symptoms: Polyneuropathy, Organomegaly, Endocrinopathy/Edema, M-protein and Skin abnormalities.

POEMS Syndrome Diagnosis

Physicians often may misdiagnose POEMS syndrome because of its rare occurrence. Specialists diagnose the condition through the detection of an overgrowth of plasma cells due to the existence of an abnormal protein in the blood or urine. The condition may also be diagnosedthrough the detection of a bone abnormality found in X-ray results or a bone marrow biopsy.

POEMS Syndrome Symptoms and Signs

Patients with POEMS syndrome have polyneuropathy, which may be painful and requires analgesia. Patients may feel an abnormal and reduced sensation and decreased power in the legs and arms. They may also have Organomegaly, Endocrinopathy/Edema, M-protein and Skin abnormalities.

POEMS Syndrome Treatment

Since POEMS syndrome is a multisystem disease, there are various options for treatment including radiation therapy, corticosteroids, chemotherapy, bone marrow transplant, hormone replacement therapy, and physical therapy. Treatment is based on the patient's needs and health issues.

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