Polyposis, Hamartomatous Intestinal
Polyposis, Hamartomatous Intestinal Causes
The condition is an inherited gene mutation passed on from parents.
Polyposis, Hamartomatous Intestinal Definition
The disease is called Peutz-Jeghers syndrome, also known as Hereditary Intestinal Polyposis Syndrome. It is an inherited condition in which hamartomatous polyps develop in the gastrointestinal tract.
Polyposis, Hamartomatous Intestinal Diagnosis
Doctors diagnose a patient as having the disease if he or she has 2 or three of the main criteria for diagnosis. History of the family having the condition, mucocutaneous lesions that cause patches of hyperpigmentation in the mouth, hands, and feet, and development of hamartomatous polyps in the gastrointestinal tract. A histological polyp sample is required for a definitive diagnosis.
Polyposis, Hamartomatous Intestinal Symptoms and Signs
Affected individuals have multiple harmartomas associated with melanin spots on the lips, buccal mucosa, and fingers. Oral pigmentation first appears and often found on the gingiva, hard palate, and inside the cheek.