Popliteal Pterygium Syndrome
Popliteal Pterygium Syndrome Causes
The syndrome is inherited due to a gene mutation (interferon regulatory factor 6). Some case of popliteal pterygium suggests new mutations due to advanced parental age.
Popliteal Pterygium Syndrome Definition
Popliteal pterygium syndrome is a condition that affects the face, limbs, and genitalia. It was named based on the popliteal pterygium, which is a weblike membrane behind the knee. The condition is also referred to as the popliteal web syndrome or facio-genito-popliteal syndrome.
Popliteal Pterygium Syndrome Symptoms and Signs
Affected individuals show varied physical anomalies in the limbs, face, or genitals such as webbings behind the knee down to the heel, malformed toenails, and webbed toes, cleft palate, or malformation of the scrotum.