Proteus Syndrome
Proteus Syndrome Causes
According to some researches, proteus syndrome is caused by an unknown gene mutated in some cells, although normal in other cells of the body; however, the real is still not defined.
Proteus Syndrome Definition
Proteus syndrome is a congenital condition characterized by skin overgrowths and abnormal bone developments, which often presents with tumors located in different parts of the body.
Proteus Syndrome Diagnosis
Careful examination of the individual with the help of imaging studies such as CT scan, Magnetic Resonance Imaging, and X-ray of the skeletal system can help in the diagnosis.
Proteus Syndrome Symptoms and Signs
Individuals suffering from proteus syndrome experience a vast majority of signs and symptoms ranging from mild to severe with the most common including: gigantism which is characterized with extreme growth of the hand, fingers, toes or feet; asymmetrical growth of limbs, body or face; overgrowth of the connective tissue on the palms of the hand or soles of the feet; darkened, elevated patches of skin; benign tumors on the skin and under the skin; extremely large and lop-sided head; and non-cancerous bony growths shooting outward from the end of bones. Other symptoms include enlargement of the spleen and spinal curvature. Characteristic facial features of an individual with proteus syndrome include: depressed nasal bridge, long and narrow face, down-slanting eyes, nostrils that are upturned, and constantly open mouth when at rest.
Proteus Syndrome Treatment
There is no treatment available that can cure proteus syndrome; treatment is based on the management of the consequences of the syndrome like surgical removal of existing tumors.