Purpura, Thrombotic Thrombocytopenic
Purpura, Thrombotic Thrombocytopenic Causes
TTP is caused by the aggregation of platelets and coagulation in the blood vessels. When the platelets are consumed during the coagulation process, it causes the shearing of red blood cells, leading to hemolysis.
Purpura, Thrombotic Thrombocytopenic Definition
Thrombotic thrombocytopenic purpura (TTP) is a rare medical condition that affects blood coagulation. The disease results to multiple blood clots in the blood vessels. This is caused by a deficiency of the enzyme ADAMTS13.
Purpura, Thrombotic Thrombocytopenic Diagnosis
TTP can be diagnosed via blood cell count and physical examination.
Purpura, Thrombotic Thrombocytopenic Symptoms and Signs
The signs and symptoms of TTP include fluctuating neurological symptoms, headaches, kidney failure, low platelet count, fever, and microangiopathic hemolytic anemia.
Purpura, Thrombotic Thrombocytopenic Treatment
Treatment for the disease include plasmapheresis, an exchange transfusion of the blood plasma. Additional immunosuppressive therapy in order to recover. However, when the disease is not treated, it can cause multiple organ failure.