Scleroderma
Scleroderma Causes
The real cause of Scleroderma is unknown. There are different predisposing factors claimed to cause Scleroderma but is still not yet clearly established.
Scleroderma Definition
Scleroderma is a rare, progressive connective tissue disorder characterized by thickening and hardening of the skin and connective tissue. Some forms of scleroderma can involve even internal organs. There are two types of scleroderma: localized scleroderma and the systemic type, known as systemic sclerosis. The localized type can be disabling but not fatal. However, the systemic type can be fatal due to complications brought about by some accompanying diseases.
Scleroderma Diagnosis
Clinical manifestations, presence of auto-antibodies and sometimes biopsy are used in diagnosis of scleroderma.
Scleroderma Symptoms and Signs
Most of the time, initial signs and symptoms presents in the skin. The following are some of the skin symptoms of Scleroderma: * Skin hardening and thickening * Shiny skin * Reddish and scaly skin * Hyper pigmentation * Finger swelling * Sclerodactyly which is defined as the hard, shiny appearance of the fingers due to excessive connective tissue build-up. * Blood vessels may tend to become visible * Painful ulcers on the fingers or toes * Calcinosis or formation of calcium deposits in any soft tissue especially near the elbows, knees or other joints. Symptoms in other Organs * Myopathy or muscle weakness * Non-specific joint pains which may cause discomfort in tendons or muscles and can lead to arthritis * Decreased ability of the lungs to transfer gases (diffusion capacity) based on pulmonary function testing. * Inflammation of the esophagus ( reflux esophagitis) * Renal involvement may include high blood pressure presenting acute organ damage evidences, high rennin levels, blood in the urine, protein loss in urine, accumulation of waste products in the urine as a result of kidney failure, destruction of red blood cells. * Cold sensitivity
Scleroderma Treatment
At present, there is no treatment available to treat Scleroderma. Treatment I most of the time directed to treat symptoms and to preserve normal body functions and minimize the occurrence of complications.