Sideroblastic Anemia, Autosomal
Sideroblastic Anemia, Autosomal Causes
Sideroblastic anemia, autosomal is caused by a genetic defect. The gene involved is an X-linked recessive gene.
Sideroblastic Anemia, Autosomal Definition
Sideroblastic anemia, autosomal is a type of sideroblastic anemia that is inherited in autosomal recessive mode of transmission. This hereditary sideroblastic anemia is a medical condition wherein the body has enough iron but cannot integrate it into hemoglobin. In this inherited form of anemia, the red blood cells become overloaded with iron thus reduce the ability of the blood to carry oxygen.
Sideroblastic Anemia, Autosomal Diagnosis
Algorithmic diagnosis of signs and symptoms in combination with some essential diagnostic workups like blood smear for red cell morphology, chemistry panel and iron-binding capacity is used as part of establishing initial diagnosis. Bone marrow examination can provide a more definitive diagnosis.
Sideroblastic Anemia, Autosomal Symptoms and Signs
Symptoms of sideroblastic anemia, autosomal might include: ? Enlarged spleen ? Liver disease or sometimes enlargement of the liver ? Pallor ? Weakness or sometimes feelings associated with fatigue ? Pigmentation in the skin ? Anemia or the decrease hemoglobin concentration in the blood ? Microcytosis or the condition marked by decreased mean cell volume of red blood cells
Sideroblastic Anemia, Autosomal Treatment
Blood transfusion is generally indicated for severe cases of sideroblastic anemia. Bone marrow transplant may be necessary for patients with primary marrow disorders. Symptomatic treatment and treatment of the underlying disease is essential part of improving the condition of the patient.