Triploid Syndrome
Triploid Syndrome Causes
The presence of an entire extra set of chromosomes cause this abnormality.
Triploid Syndrome Definition
This disorder is an extremely rare chromosomal disorder. Affected individuals have 3 chromosomes for a total of sixty-nine rather than the normal 46 chromosomes. Unborn children with Triploid syndrome are usually lost through early miscarriage but those who make it survive for as long as five months.
Triploid Syndrome Diagnosis
Diagnosis is made by physical examination shortly after birth. Chromosome analysis or karyotyping will confirm the diagnosis. During pregnancies, abnormalities can be seen through sonograms. Other tests include abnormal screening test, or an abnormal CVS or amniocentesis test.
Triploid Syndrome Symptoms and Signs
Among fetuses, a sonogram can reveal severe growth problems or intrauterine growth retardation (IUGR), abnormal placenta, and limb abnormalities. Other abnormal findings when using the sonogram include brain abnormalities, cleft lip and possible cleft palate, heart defects, kidney abnormalities, abdominal wall defects, neural tube defects, oligohydramnios, and placental abnormalities.
Triploid Syndrome Treatment
Surviving infants need palliative care. It is the only means to manage the disease since there really is no cure for triploid. Nourishment, warmth, and comfort should be given to the infant since surgical correction of birth defects is not suggested since the disease has a lethal nature. Pregnant mothers can choose to abort the pregnancy but for those who want to go on with it, the mother should be monitored for pre-eclampsia and hyperthyroidism.