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Trophoblastic Neoplasms



Trophoblastic Neoplasms Causes


Choriocarcinoma may be uncommon but it is usually curable. As a cancer that can be associated with pregnancy, it forms in the tissues that develop after a baby is conceived. Choriocarcinoma looks like the cells that normally surround a developing baby and approximately 50% of cases of those who have the disease had a hydatidiform mole (molar pregnancy). Almost one-fourth of choriocarcinomas occur after pregnancy has resulted in the delivery of a normal child. The rest of the cases occur after any type of abortion, ectopic pregnancy, or genital tumor.


Trophoblastic Neoplasms Definition


Gestational trophoblastic disease or also known as Trophoblastic neoplasms is a quick growing form of cancer that occurs in a woman's uterus after a pregnancy, miscarriage, or abortion. The disease is usually metastatic, which means it spreads to other places in the body. It is also known as choriocarcinoma.


Trophoblastic Neoplasms Diagnosis


Pelvic examinations may reveal continued uterine enlargement or a tumor. It may be felt within the genitor-urinary tract. Tests include quantitative serum HCG, CT scan and chest x-ray.


Trophoblastic Neoplasms Symptoms and Signs


Continued vaginal bleeding is a possible symptom in women with a recent history of hydatidiform mole, abortion, or pregnancy. Other symptoms include irregular vaginal bleeding, certain types of cysts on the ovaries, uneven swelling of the uterus, persistently high HCG levels, and pain.


Trophoblastic Neoplasms Treatment


Careful history and examination are done to rule out metastasis (spread to other organs) after the initial diagnosis. Just like other forms of cancer, chemotherapy is the treatment of choice and a hysterectomy is rarely required.


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