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ZAP70 Deficiency

ZAP70 Deficiency Causes

The deficiency is due to a lack of CD8+ T cells and the presence of circulating CD4+ T cells that are unresponsive to T-cell receptor-mediated stimuli.

ZAP70 Deficiency Definition

ZAP70 deficiency, the short term used for zeta-chain-associated protein 70 kD deficiency, is a rare and severe combined immunodeficiency.

ZAP70 Deficiency Treatment

ZAP70 deficiency genetically inherited. It cannot be cured but gene therapy proposed.

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